This is an 80's movie which mixes the Jekyll and Hyde story with the body horror sub genre that was popular at the time of this movies release. An aged actress desperate to maintain her youth has been funding a scientist who has been trying to create a serum to reverse the ageing process. Well the acting granny has gotten bored with waiting and demands he tests his serum on her. Had she seen the doctors collection of deformed lab rats she may have reconsidered. Well the serum works for a while but then her head gets big and pulsating. He tries to rectify it but obviously it doesn't work out, cue blood and gore.
I really like this movie. It has great old school prosthetic effects some pretty cool music and acting that's not that bad. It has a few of those odd things that make a movie memorable like the night watch man who has the voice of a cartoon character, the fact all the scientists constantly refer to each other as doctor In every conversation. Also nearly everyone in this film has a secret crush on someone. The main woman when she starts transforming nearly always does a really dramatic spin either away from the camera or towards it with her hands in a startled pose. I find these sort of things endearing in a movie and they make it more likable despite its obvious short comings.
If you like these 80's horrors this is definitely worth seeking out and the end gore sequence is just brilliant.
Review by Greenzombidog from the Internet Movie Database.